You are here

Lead Identification

Our chemical start points are identified predominantly from HTS. We have built a high quality compound collection and the ability to screen it efficiently, exploiting the endpoint best suited to each target. With the re-emergence of cell-based and pathway screening, we continue to develop our in-house expertise in cell-based HTS and molecular target identification. We encourage collaborating academics to actively contribute to assay development and target de-convolution. We demonstrate target engagement as early as possible using structural biology and various other biophysical techniques. High quality data supports timely decision making, and our work is underpinned by informatics capabilities that allow us to process, store, track, and interrogate large datasets.