Careers

Screening and Compound Profiling, Scientist and Senior scientist

Screening and Compound Profiling, Scientist and Senior scientist Salary Closes
Babraham Reserach Campus, Cambridge
Maternity Cover, full time
Dependent on experience Friday, October 19, 2018

Interviews will start as early as 1st October so early application is encouraged.

 

Cancer Research UK's Therapeutic Discovery Laboratories (CRUK-TDL) is the in-house CRUK drug discovery unit with a principal focus on establishing and prosecuting biologically-themed multi-project alliances with industry.  Based at the Babraham Research Campus, Cambridge, and the London Bioscience Innovation Centre, London, TDL comprises over 80 staff from both industrial and academic backgrounds.

 

We are currently recruiting for two positions, a Senior Scientist and a Scientist, to join CRUK-TDL’s Discovery Bioscience Screening and Compound Profiling team to characterise small molecules in vitro.

 

At CRUK-TDL, we bring together the best minds in basic and clinical cancer research, the rigour and drive of pharmaceutical and biotech companies, and our in-house drug discovery and alliance management capabilities to deliver breakthrough medicines for cancer patients

In recent years, we have established successful alliances with AstraZeneca, Teva Pharmaceuticals, FORMA Therapeutics, Merck KGaA, LifeArc and Celgene.  We have also been successful in implementing the alliance model through the formation of spin-out companies, including Artios and iOnctura.

 

Our laboratories house the personnel and equipment to progress projects from initial hypothesis through to selection of candidate drugs.  We couple this with a deep understanding of academic and industrial drivers enabling us to build alliances that satisfy the curiosity of basic research and the rigour of drug discovery.

 

Ref 10631a Senior scientist: biochemical assays

This position will focus on the development of biochemical assays using recombinant proteins and a range of assay technologies (such as fluorescence intensity and polarisation, FRET, and luminescence) to be used in high throughput screening and support chemistry expansion and characterisation of hit compounds.

  • A detailed understanding of enzymology is essential.
  • Any experience of using automation would be an advantage.

This role would suit an MSc or PhD graduate, or someone with an equivalent level of experience, with at least three years’ experience of assay development, preferably in a drug discovery environment.

To see a full job description please click here.

 

Ref 10631b Scientist: cell assays

This position will focus on characterising compounds in cell-based assays such as proliferation, ELISA and gene reporter assays.

  • Cell culture experience is essential.
  • Any experience of using automation would be an advantage. 

This role would suit an MSc or PhD graduate, or someone with an equivalent level of experience. Experience of working in a drug discovery environment would be an advantage.

To see a full job description please click here.

 

The successful applicants will form an integral part of the CRUK-TDL team working alongside our industry and academic partners to progress novel cancer targets towards patient benefit. Both roles require:

  • Excellent communication and interpersonal skills
  • The ability to work well in a team
  • Strong organisation skills and attention to detail

 

Please submit your CV and Cover Letter online with confirmation of your preferred role.

Please see following link to apply: https://cancerresearchuk.wd3.myworkdayjobs.com/External_Careers/job/CRT-Cambridge-Babraham/Scientist---Senior-Scientist_R010631