Gerard Evan

Professor of Biochemistry and Head of Department, University of Cambridge

Gerard Evan studied Biochemistry at St Peter’s College, Oxford, migrating to Cambridge as a graduate student at King’s College and working for his Ph.D. on tumour immunology at the MRC Laboratory of Molecular Biology. He was then an MRC travelling fellow in the laboratory of Nobel Laureate J. Michael Bishop at the University of California San Francisco (UCSF), where he developed his life-long interest in the molecular biology of cancer. After UCSF, he returned briefly to Cambridge as a research fellow at Downing College before being recruited in 1988 as a Principal Scientist at the Imperial Cancer Research Fund Laboratories in London, contemporaneously holding Royal Society’s Napier Chair of Cancer Research at UCL. In 1999, he was recruited back to California as the Gerson and Barbara Bass Bakar Distinguished Professor of Cancer Research at UCSF but, after 11 years of unyielding sunshine, mountains and natural beauty he returned in 2009 to Cambridge to become the Sir William Dunn Professor and Head of Biochemistry. Gerard was elected to EMBO in 1996, the UK Academy of Medical Sciences in 1999, the Royal Society in 2004, the European Academy of Sciences in 2006 and the European Academy of Cancer Sciences in 2013. His research, which is funded by Cancer Research UK, is focused on defining the molecular aberrations that underpin cancers, with a particular focus on tumors of lung, pancreas and brain. His research makes use of state-of-the-art switchable genetic mouse models as well as wide variety of molecular and biochemical approaches to determine the mechanism of action of the four great oncogenic signaling hubs – Ras, Myc, E2F and p53.